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Home - Products - Proteasome/Ubiquitin - Serine Protease - Gabexate mesylate

Gabexate mesylate

CAS No. 56974-61-9

Gabexate mesylate( —— )

Catalog No. M15075 CAS No. 56974-61-9

Gabexate Mesylate is a Factor X inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 46 In Stock
10MG 74 In Stock
25MG 122 In Stock
50MG 178 In Stock
100MG 291 In Stock
200MG 379 In Stock
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Biological Information

  • Product Name
    Gabexate mesylate
  • Note
    Research use only, not for human use.
  • Brief Description
    Gabexate Mesylate is a Factor X inhibitor.
  • Description
    Gabexate Mesylate is a Factor X inhibitor.
  • In Vitro
    Cell Proliferation Assay Cell Line:HepG2 cells Concentration:100, 300, and 1000 μM Incubation Time:72 hours Result:The proliferation rate decreased in a dose-dependent manner.
  • In Vivo
    Animal Model:Male Sprague-Dawley rats (100-120 g) with spinal nerve ligation (SNL) Dosage:20 mg/kg Administration:Intraperitoneally; daily; from 3rd day until the 14th day Result:Showed a higher PWT than those of the vehicle-treated group. Markedly decreased the expression of p65. Attenuated the expressions of IL-1, IL-6, and TNF-α at 7th day.
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Serine Protease
  • Recptor
    Serine Protease
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    56974-61-9
  • Formula Weight
    417.48
  • Molecular Formula
    C17H27N3O7
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 83 mg/mL (198.81 mM); Water: 12 mg/mL (28.74 mM); DMSO: 83 mg/mL (198.81 mM)
  • SMILES
    CS(O)(=O)=O.CCOC(=O)C1=CC=C(OC(=O)CCCCCN=C(N)N)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Erba F, et al. Biochem Pharmacol. 2001 Feb 1;61(3):271-6.
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